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  • More
    • HOME
    • ABOUT US
    • TUMOR IMMUNE THERAPY
      • Introduction
      • Cancer Immunotherapy Type
    • NBRL CELL & GENE DRUG R&D
      • Introduction
      • NBRL Cell & Gene Drug
      • Intrabody Development
      • Alzheimer’s Disease
      • Next Step Development
    • CONTACT US
  • HOME
  • ABOUT US
  • TUMOR IMMUNE THERAPY
    • Introduction
    • Cancer Immunotherapy Type
  • NBRL CELL & GENE DRUG R&D
    • Introduction
    • NBRL Cell & Gene Drug
    • Intrabody Development
    • Alzheimer’s Disease
    • Next Step Development
  • CONTACT US

NBRL Developed Cell/Gene Drug Candidates

 

NBRLBoston has been developing the novel anti-tumor immune gene mRNA/DNA combo with iPS derived universal NK and T cells, and steam cell based therapeutic candidates,  and TCRm and CAR NK candidates that are the highest level of innovative research and development  for anti-cancer immune drugs development. 


Our developed anti solid tumor mRNA/DNA  gene drug combo with human PBMC derived T and NK cell therapeutic candidates have  demonstrated strong efficacy on the inhibition of solid tumor growth in vitro and in vivo studies by improving cytotoxicity T  and NK  killing tumor cell function, blocking negative signals, and specializing in the tumor micro-environment normalization through the balance of various cytokines/immune cells/blood supply etc. involved in immune activity against tumor.

NBRLBio mRNA/DNA Drug Killing Cancer Cell Mechanism

NBRLBoston Has Developed Novel Anti-Cancer mRNA/DNA Based Drug Targeting Pathway

  • A)  Targeting tumor cell and tumor vessel surface antigens
  • B)  Activating cytokines
  • C)  Blocking immune check point inhibition pathway(release brake)
  • D) Stimulating immune check point stimulation pathway(step-on gas pedal)
  • E) Improving/normalizing tumor microenvironment to enhance T cell and NK cell killing cancer cells
  • F) Inhibiting/converting negative T regular cell

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